人CD26抗原产品介绍(中英文版） 品牌：原鑫生物 货号：CU69 规格：10ug-100ug/￥1200   立即购买

Recombinant Human DPPIV/CD26 

人CD26抗原产品介绍(中英文版）

人CD26抗原产品介绍产品说明(Description)

Recombinant Human Dipeptidyl Peptidase 4 is produced by our Mammalian expression system and the target gene encoding Asn29-Pro766 is expressed with a Fc tag at the N-terminus. 

Accession #: P27487

Known as: Dipeptidyl peptidase 4; ADABP; Adenosine deaminase complexing protein 2; ADCP-2; Dipeptidyl peptidase IV; DPP IV; T-cell activation antigen CD26

人CD26抗原产品介绍制剂（Formulation）

Supplied as a 0.2 μm filtered solution of PBS, pH7.4.

人CD26抗原产品介绍质量控制（Quality Control） 

Purity: Greater than 95% as determined by reducing SDS-PAGE.    

Endotoxin: Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

人CD26抗原产品介绍运输(Shipping)

The product is shipped on dry ice/polar packs. 

Upon receipt, store it immediately at the temperature listed below.

人CD26抗原产品介绍保存(Storage)

Store at ≤-70°C, stable for 6 months after receipt.

Store at ≤-70°C, stable for 3 months under sterile conditions after opening. 

Please minimize freeze-thaw cycles.   

人CD26抗原产品介绍背景（Background）

CD26 is a signal-anchor for type II membrane protein that belongs to the peptidase S9B family. CD26 is expressed specifically in lymphatic vessels but not in blood vessels in the skin, small intestine, esophagus, ovary, breast and prostate glands. It acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. It’s binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. It may be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, it enhanced cell proliferation, a process inhibited by GPC3. It acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the cir

产品说明(（描述）

重组人二肽基肽酶4由我们的哺乳动物表达系统产生，编码Asn29-Pro766的靶基因在N末端用Fc标签表达

加入#：P27487

称为：二肽基肽酶4；ADABP公司；腺苷脱氨酶复合蛋白2；ADCP-2型；二肽基肽酶IV；民进党四号；T细胞活化抗原CD26

制剂（（配方）

作为0.2μm PBS过滤溶液提供，pH7.4。

质量控制（质量控制）

纯度：经还原SDS-PAGE测定大于95%。   

内毒素：经鲎试剂检测，小于0.1ng/ug（1eu/ug）。

运输(运输）

产品采用干冰/极地包装运输

收到后，立即在下列温度下储存。

保存(储存）

储存于≤-70°C，收到后稳定6个月。

储存于≤-70°C，打开后在无菌条件下稳定3个月

请尽量减少冻融循环

背景（背景）

CD26是肽酶S9B家族Ⅱ型膜蛋白的信号锚定。CD26在淋巴管中特异表达，但在皮肤、小肠、食管、卵巢、乳腺和前列腺的血管中不表达。它通过至少结合ADA、CAV1、IGF2R和PTPRC作为T细胞共激活的正调节因子。它与CAV1和CARD11结合，以T细胞受体/CD3依赖的方式诱导T细胞增殖和NF-κB活化。它与ADA的相互作用也调节淋巴细胞与上皮细胞的粘附。FAP参与细胞外基质（ECM）的细胞周蛋白水解，内皮细胞向ECM的迁移和侵袭。它可能参与促进淋巴管内皮细胞粘附、迁移和小管形成。当过表达时，它促进细胞增殖，这一过程被GPC3抑制。它也是一种丝氨酸外肽酶，具有二肽基肽酶活性，通过切割cir中的肽来调节各种生理过程

人CD26抗原产品链接：http://www.shyx-bio.com/products-284.html